Catalog No.
CS036016
Species reactivity
Human
Applications
Research Grade Biosimilar
Host species
Humanized
Isotype
IgG1-kappa
Expression system
Mammalian Cells
Clonality
Monoclonal
Target
Transferrin receptor protein 1, TfR1, T9, Trfr, p90, CD71, TFRC, TfR, sTfR, TR
Concentration 1mg/mlEndotoxin level
Please contact the lab for this information.
Purity
>95% purity as determined by SDS-PAGE.
Purification
Protein A/G, purified from cell culture supernatant.
Accession
P02786
Form
Liquid
Storage buffer
0.01M PBS,pH7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -137°C.
Alternate Names
JR-141,CAS:2140211-48-7
Background
Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice.
Note
For research use only. Not for use in clinical or therapeutic applications.
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