Catalog No. 

CS112016

Species reactivity

Human

Applications 

Research Grade Biosimilar

Host species 

Chimeric

Isotype 

IgG1-kappa

Expression system 

Mammalian Cells

Clonality 

Monoclonal

Target

INSR, IR, CD220, Insulin receptor

Concentration 

1mg/ml

Endotoxin level 

Please contact the lab for this information.

Purity

>95% purity as determined by SDS-PAGE.

Purification 

Protein A/G, purified from cell culture supernatant.

Accession 

P06213

Form

Liquid

Storage buffer 

0.01M PBS,pH7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -510°C.

Alternate Names 

AGT-181,HIRMAb-IDUA,CAS:1815583-32-4

Background 

Valanafusp alfa (AGT-181) is a chimeric monoclonal antibody that fuses human α-L-iduronidase (IDUA) and targets the human insulin receptor (HIR). Valanafusp alfa has brain penetrating properties, making it useful for research on mucopolysaccharidosis type I (MPS I).

Note 

For research use only. Not for use in clinical or therapeutic applications.