Catalog No.

CS977036

Species reactivity

Human

Applications

Research Grade Biosimilar

Host species

Humanized

Isotype

IgG4-kappa

Expression system

Mammalian Cells

Clonality

Monoclonal

Target

Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB, GARP, Leucine-rich repeat-containing protein 32, Glycoprotein A repetitions predominant, D11S833E, Garpin, Transforming growth factor beta activator LRRC32, LRRC32

Concentration

0.81mg/ml

Endotoxin level

Please contact the lab for this information.

Purity

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G, purified from cell culture supernatant.

Accession

P01137 & Q14392

Form

Liquid

Storage buffer

0.01M PBS,pH7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -753°C.

Alternate Names

Bispecific,ABBV-151,ARGX-115,MHG-8,MHGARP-8,PR-1762844CAS:2412004-88-5

Background

Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors.

Note

For research use only. Not for use in clinical or therapeutic applications.