Catalog No. 

CS782126

Species reactivity 

Human

Applications 

Research Grade Biosimilar

Host species 

Humanized

Isotype 

IgG1-kappa

Expression system 

Mammalian Cells

Clonality 

Monoclonal

Target

Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40, Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA

Concentration 

1mg/ml

Endotoxin level 

Please contact the lab for this information.

Purity 

>95% purity as determined by SDS-PAGE.

Purification 

Protein A/G, purified from cell culture supernatant.

Accession

P25942 & Q07011

Form

Liquid

Storage buffer 

0.01M PBS,pH7.4.

Stability and Storage 

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -752°C.

Alternate Names 

Bispecific,BNT-312,DuoBody-CD40x-4-1BB,GEN1042,GEN-1042,GEN1042CAS:2253891-70-0

Background 

Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity.

Note 

For research use only. Not for use in clinical or therapeutic applications.