Malotilate (NKK 105), an orally active hepatotropic agent and an anti-fibrotic substance, selectively inhibits the 5-lipoxygenase (5-LOX) (IC50=4.7 μM). Malotilate prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing the retention of transferrin in the hepatocytes
IC50 & Target:5-Lipoxygenase,4.7 μM (IC50)
分子量:288.38
Formula:C12H16O4S2
CAS 号:59937-28-9
性状:固体
颜色:Light yellow to yellow
中文名称:马洛替酯;二噻茂醋
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Powder -20°C 3 years;4°C 2 years