产品展厅
LY402913
2023-02-21
产品详情
- 产地 China
- Cas:246238-55-1
- 价格:1298
- 产品名称LY402913
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- 简介
产品描述
LY402913 is a selective modulators of the multidrug resistance protein (MRP1).
体外活性
LY402913 demonstrated reversal of MRP1-mediated drug resistance (in the presence of a sublethal dose of doxorubicin) in the MRP1-transfected cell line, HeLa-T5, EC50 = 0.90[1].
Cas No.
246238-55-1
分子式
C28H24ClN3O6
分子量
533.96
参考文献
[1]Norman BH, Lander PA, Gruber JM, Kroin JS, Cohen JD, Jungheim LN, Starling JJ, Law KL, Self TD, Tabas LB, Williams DC, Paul DC, Dantzig AH. Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1). Bioorg Med Chem Lett. 2005 Dec 15;15(24):5526-30. doi: 10.1016/j.bmcl.2005.08.075. Epub 2005 Oct 3. PMID: 16202586.
储存和溶解度
( < 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Note
For research use only .
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