产品展厅
MST-312
2023-02-21
产品详情
- 产地 China
- Cas：368449-04-1
- 价格：417
- 产品名称MST-312
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- 简介
产品描述
MST-312 is an inhibitor of telomerase and can be used in studies about cancer, such as multiple myeloma.
体外活性
In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner[1].
Cas No.
368449-04-1
分子式
C20H16N2O6
分子量
380.356
别名
Telomerase Inhibitor IX
参考文献
[1]Ameri Z, et al. Telomerase inhibitor MST-312 induces apoptosis of multiple myeloma cells and down-regulation of anti-apoptotic, proliferative and inflammatory genes. Life Sci. 2019;228:66-71.
储存和溶解度
DMSO:70 mg/mL (184.04 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Note
For research use only .
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