ML 348 (GNF-Pf-1127) 是一种选择性和可逆的酰基蛋白硫酯酶 1 (APT1)/溶血磷脂酶 1 (LYPLA1) 抑制剂,IC50 为 210 nM,几乎不抑制 LYPLA2。
Cas No.
899713-86-1
SDF
别名
GNF-Pf-1127
化学名
N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-(furan-2-carbonyl)piperazin-1-yl)acetamide
Canonical SMILES
ClC1=C(NC(CN2CCN(C(C3=CC=CO3)=O)CC2)=O)C=C(C(F)(F)F)C=C1
分子式
C18H17ClF3N3O3
分子量
415.79
溶解度
≥ 19.1mg/mL in DMSO
储存条件
Store at -20°C
General tips
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
Note:仅用于科学研究,不为任何个人或者非科研性质的用途提供产品和服务。