KT 5823 是一种选择性 cGMP 依赖性蛋白激酶 (PKG) 抑制剂,Ki 值为 0.23 μM,它还抑制 PKA 和 PKC,Ki 值分别为 10 μM 和 4 μM。
Cas No.
126643-37-6
SDF
别名
蛋白激酶仰制剂KT5823
化学名
(5S,6S,8S)-methyl 6-methoxy-5,14-dimethyl-13-oxo-6,7,8,13,14,15-hexahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanodibenzo[b,h]cycloocta[jkl]cyclopenta[e]-as-indacene-6-carboxylate
Canonical SMILES
O=C([C@@]([C@]1(C)O[C@@H]2N3C4=C5N1C6=CC=CC=C6C5=C(CN(C)C7=O)C7=C4C8=CC=CC=C38)(C2)OC)OC
分子式
C29H25N3O5
分子量
495.53
溶解度
1mg/mL in ethyl acetate or 20mg/mL in DMSO
储存条件
Desiccate at -20°C
General tips
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request