产品展厅
产品展厅
Decitabine(NSC127716, 5AZA-CdR) (NSC 127716) 是一种具有口服活性的脱氧胞苷类似物抗代谢物和 DNA 甲基转移酶抑制剂。 Decitabine (NSC127716, 5AZA-CdR) 结合到 DNA 中代替胞嘧啶可以将 DNA 甲基转移酶共价捕获到 DNA 上，导致酶的不可逆抑制。 Decitabine(NSC127716, 5AZA-CdR) 诱导细胞 G2/M 期阻滞和细胞凋亡。 Decitabine (NSC127716, 5AZA-CdR) 具有有效的 活性。
| Cas No. | 2353-33-5 | SDF | |
| 别名 | 地西他滨; 5-Aza-2'-deoxycytidine; 5-AZA-CdR; NSC 127716 | ||
| 化学名 | 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one | ||
| Canonical SMILES | C1C(C(OC1N2C=NC(=NC2=O)N)CO)O | ||
| 分子式 | C8H12N4O4 | 分子量 | 228.08 |
| 溶解度 | ≥ 11.4 mg/mL in DMSO, ≥ 23.3 mg/mL in Water with gentle warming | 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. | ||
| Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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