产品展厅
产品展厅
体外活性:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
分子式:
C21H25F3N4O8
分子量:
518.446
别名:
Thalidomide-NH-PEG2-C2-NH2 TFA
参考文献:
[1]Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
储存和溶解度:
( < 1 mg/ml refers to the product slightly soluble or insoluble )In solvent: -80°C for 2 years
Note:
For research use only .
