Pomalidomide-PEG3-C2-NH2 TFA 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Pomalidomide 的 cereblon 配体和 3 个单元 PEG 的 linker。

生物活性：
Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

IC50 & Target[1]：
Cereblon

分子量：
562.49

Formula：
C23H29F3N4O9

CAS 号：
2414913-97-4

运输条件：
Room temperature in continental US; may vary elsewhere.

储存方式：
4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

参考文献:
[1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.  Content Brief

Note：
For research use only .