产品描述
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respiratory tract, improving fever and nasal inflammation.
别名
2'-氟脱氧鸟苷 , 2'-脱氧-2'-氟鸟苷 ,
纯度
98%
分子量
285.23
分子式
C10H12FN5O4
CAS No.
78842-13-4
存储
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
溶解度
DMSO: 50 mg/mL (175.30 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
参考文献
1. Jakeman KJ, et, al. Efficacy of 2'-deoxy-2'-fluororibosides against influenza A and B viruses in ferrets. Antimicrob Agents Chemother. 1994 Aug;38(8):1864-7.
2. Tisdale M, et, al. Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine. Antimicrob Agents Chemother. 1995 Nov;39(11):2454-8.
Note
For research use only.
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