产品名称：AF488 醛 *与 Alexa Fluor™ 488 醛的结构相同*

规格：1mg

储存条件：保存在冰箱-15℃干燥

保质期：12个月

产品物理化学光谱特性

分子量：750.75

外观：固体

溶剂：DMSO

激发波长(nm)：499

发射波长(nm)：520

产品介绍

AF488 由 AAT Bioquest 生产，与 Alexa Fluor® 488 具有相同的化学结构（Alexa Fluor® 是 ThermoFisher 的商标）。 AF488 醛含有 XFD488 的荧光团。 它是一种活性绿色荧光染料，可与胺、肼或羟胺反应。 醛基对 pH 5-9 的胺、酰肼或羟胺基具有反应性。 与胺反应性琥珀酰亚胺酯基团 (NHS) 不同，醛可以在酸性 pH 下与 N 端胺基反应，某些生物偶联反应有时需要这种条件。 醛与胺基反应形成中间席夫键。 用氢化物进一步还原将形成稳定的 C-N 键。 醛和其他基团之间的反应允许荧光素染料在目标分子上的所需位置进行位点特异性结合和标记。  AF488 染料可以通过 FITC 通道下的普通荧光仪器轻松检测。

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