6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo^{[1] [2]} .

6-Methyluracil (50 mg/kg; a single i.p.) produces a pronounced radioprotective effect in BALB and SHK mice^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

126.11

C?H?N?O?

626-48-2

6-甲基尿嘧啶；2,4-二羟基-6-甲基嘧啶

O=C1NC(C=C(C)N1)=O

Room temperature in continental US; may vary elsewhere.

• [1]. Cromby CH, et, al. 6-Methyluracil excretion in 2-methylacetoacetyl-CoA thiolase deficiency and in two children with an unexplained recurrent ketoacidaemia. J Inherit Metab Dis. 1994;17(1):81-4.

  [2]. Taran IP, et, al. [The antiradiation action of 6-methyluracil]. Radiobiologiia. Mar-Apr 1993;33(2):285-90.