NGB 2904 hydrochloride
2021-03-10
产品详情
- Cas：189061-11-8
- 价格：3000
- 产品名称NGB 2904 hydrochloride
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- 简介
NGB 2904 hydrochloride is a potent, selective, orally active and brain-penetrated antagonist of?dopamine D3 receptor, with a?Ki?of 1.4 nM. NGB 2904 hydrochloride shows selectivity for D3 over D2, 5-HT2, α1, D4, D1 and D5 receptors (Kis=217, 223, 642, >5000, >10000 and >10000 nM, respectively). NGB 2904 hydrochloride antagonizes Quinpirole-stimulated mitogenesis. NGB 2904 hydrochloride can inhibit Cocaine's rewarding effects and Cocaine-induced reinstatement of drug-seeking behavior
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