DL-TBOA ammonium
2021-03-10
产品详情
- Cas:2093503-71-8
- 价格:3000
- 产品名称DL-TBOA ammonium
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- 简介
DL-TBOA ammonium is a potent non-transportable inhibitor of?excitatory amino acid transporters?with?IC50s of 70 μM, 6 μM and 6 μM for?excitatory amino acid transporter-1 (EAAT1),?EAAT2?and?EAAT3, respectively. DL-TBOA ammonium inhibits the uptake of [14C]glutamate in COS-1 cells expressing the human?EAAT1?and?EAAT2?with?Ki?valuesof 42 μM and 5.7 μM, respectively. DL-TBOA ammonium blocks?EAAT4?and?EAAT5?in a competitive manner with?Ki?values of 4.4 μM and 3.2 μM, respectively
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