hSMG-1 inhibitor 11j
2021-03-10
产品详情
- Cas:1402452-15-6
- 价格:3000
- 产品名称hSMG-1 inhibitor 11j
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- 简介
hSMG-1 inhibitor 11j, a pyrimidine derivative, is a potent and selective inhibitor of?hSMG-1, with an?IC50?of 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over?mTOR?(IC50=50 nM),?PI3Kα/γ?(IC500=92/60 nM) and?CDK1/CDK2?(IC50=32/7.1 μM). hSMG-1 inhibitor 11j can be used for the research of cancer
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