Benzoctamine hydrochloride (Ba-30803) is a psychoactive agent with anti-anxiety effect. Benzoctamine hydrochloride blocks the central postsynaptic serotonin receptors and decreases 5-HT turnover in the brain^{[1] [2]} .

Benzoctamine hydrochloride (Ba-30803) inhibits the head twitch reaction induced by L-5-hydroxytryptophan (5-HTP) in mice and by 5-methoxytryptamine (5-MT) in rats pretreated with tranylcypromine. Benzoctamine also antagonizes tryptamine (TRP)-induced clonic convulsions of forepaws in rats ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

285.81

C??H??ClN

10085-81-1

CNCC12C3=C(C=CC=C3)C(CC2)C4=CC=CC=C14.[H]Cl

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Lippmann W, et al. Effects of benzoctamine and chlordiazepoxide on turnover and uptake of 5-hydroxytryptamine in the brain. Br J Pharmacol. 1974;51(4):571-575.

  [2]. Przegaliński E, et al. On the central antiserotonin activity of benzoctamine and opipramol. Pol J Pharmacol Pharm. 1978;30(6):781-790.