产品展厅
产品展厅
| Description |
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1] . |
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| IC50 & Target |
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| In Vitro |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] . MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| In Vivo |
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| Molecular Weight |
528.55 |
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| Formula |
C??H??N?O? |
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| CAS No. |
1037589-69-7 |
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| SMILES |
O=C(CCN1C(C=CC1=O)=O)NCCOCCOCCC(NC2=CC=C(C=C2)CCC(N3C(CC3)=O)=O)=O |
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| Shipping |
Room temperature in continental US; may vary elsewhere. |
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| Storage |
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| Solvent & Solubility |
In Vitro:
DMSO : 125 mg/mL (236.50 mM; Need ultrasonic)
Preparing
Stock Solutions
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
In Vivo:
请根据您的实验动物和给药方式 选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：
——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
*以上所有助溶剂都可在 MCE 网站选购。
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| References |
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