货号（Catalog No.）

CSD00202

通用名INN

Rovelizumab

纯度(Purity)

>95%

浓度( Concentration)

1mg/ml

Formulation

PBS buffer PH7.5

Source

CHO cells

内毒素(Endotoxin level)

Please contact with the lab for this information.

生物活性

别名(Alternative names)

Hu23F2G

靶点;物种(Specificity target name;species)

ITGAL/CD11a/ITGB2/CD18[Homo sapiens]

活性研究（体外/体内研究）(Activity in vitro)

Lifitegrast is a novel small molecule integrin antagonist that inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), thus lessening overall inflammatory responses. Lifitegrast strongly inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM.

种类(Species)

Humanized

受体鉴定(Receptor identification)

IgG4-nd

化学信息

CAS

339086-79-2

存储条件(Storage)

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.

Note

For research use only .