Certolizumab Pegol ( 赛妥珠单抗 )

产品货号：CSD00153

类别：单克隆抗体药物类似物

靶点;物种(Specificity target name;species)：TNFSF2/TNF-alpha/TNFA[Homo sapiens]

种类(Species)：Humanized

受体鉴定(Receptor identification)：Fab'-G1-kappa

货号（Catalog No.）

CS00153

通用名INN

Certolizumab Pegol

纯度(Purity)

>95%

浓度( Concentration)

1mg/ml

Formulation

PBS buffer pH7.5

Source

CHO cells

内毒素(Endotoxin level)

Please contact with the lab for this information.

产品描述(Description)

Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha).1 It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. The absence of the Fc region was ideated to prevent complement fixation and antibody-mediated cytotoxicity as well as to markedly increase its half-life.

别名(Alternative names)

CDP870,PHA-738144

靶点;物种(Specificity target name;species)

TNFSF2/TNF-alpha/TNFA[Homo sapiens]

种类(Species)

Humanized

受体鉴定(Receptor identification)

Fab'-G1-kappa