产品描述

Licoisoflavone A is a potential MRP inhibitor, it shows inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro.

靶点活性

MRP

体外活性

We present the results of an in vitro investigation of the inhibitory effects of licoisoflavones A and B and sophoraisoflavone A isolated from Sophra mooracroftiana BETH ex BAKER on copper-induced protein oxidative modification of mice brain homogenate in vitro. Although inhibitory effect of sophoraisoflavone A was stronger than those of licoisoflavones A and B, genistein as a related isoflavone, and mannitol as a hydroxy radical scavenger, inhibitory effects of licoisoflavones A and B were weaker than those of genistein and mannitol.

别名

甘草异黄酮甲 , 甘草异黄酮 A

纯度

≥95%

分子量

354.4

分子式

C20H18O6

CAS No.

66056-19-7

存储

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

参考文献

1. Inhibitory effects of licoisoflavones A and B and sophoraisoflavone A of Sophra mooracroftiana Beth ex Baker on copper-ion-induced protein oxidative modification of mice brain homogenate, in vitro.Biol Trace Elem Res. 2001 Aug;81(2):169-75.

Note

For research use only.